How do I solve 22 down in Times Cryptic 29563?

Question

Accepted Answer

22 down reads "Load vehicle and set off" (5 letters); the answer is CARGO. It's a charade: the answer breaks into parts in clue order, each part clued by a word or short phrase. No indicators needed; watch for standard abbreviations (RA = artist, US = American, IN = at home) and short synonyms. The full step-by-step breakdown is on this page.

Load vehicle and set off (5)

22D — Load vehicle and set off (5) — CARGO